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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4B All Species: 22.42
Human Site: S407 Identified Species: 32.89
UniProt: Q2VIQ3 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2VIQ3 NP_001092763.1 1234 140035 S407 E K L S R C L S K A A G Q T A
Chimpanzee Pan troglodytes XP_518055 1227 139177 S407 E K L S R C L S E A A G Q T A
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 S407 E K L S R G L S E A A G Q T A
Dog Lupus familis XP_549061 1234 139874 S408 E K L S R G L S E A A G Q T A
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 S408 E K L S R G L S E A A G Q T A
Rat Rattus norvegicus Q7M6Z5 1394 158861 E416 L G Y Q D C I E Q A F A F L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 S410 E K L S R G L S E A A G Q T A
Frog Xenopus laevis Q91784 1226 138905 G408 G K L S R E L G E A A V Q T A
Zebra Danio Brachydanio rerio Q58G59 1363 154819 E466 S G L D S G I E S S S T E D S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 F103 E G F N G C I F A Y G Q T G T
Honey Bee Apis mellifera XP_395595 1064 123475 K377 E H Q E L E A K N Q C L Q K K
Nematode Worm Caenorhab. elegans P46873 699 78760 E18 C R P F N Q R E K D L N T T L
Sea Urchin Strong. purpuratus P46872 699 78679 R18 V R V V V R C R P L N S K E T
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 S354 Q D S L G G N S R T V M I A C
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_200901 1294 145204 Q424 R E L H N E L Q E R R V A S E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 A247 E K V G K T G A S G Q T L E E
Conservation
Percent
Protein Identity: 100 97.9 90.9 91 N.A. 83.6 26.4 N.A. N.A. 71.3 66.6 25.1 N.A. 27.2 36.8 25.6 27.4
Protein Similarity: 100 98.8 94 94.7 N.A. 90.3 47.2 N.A. N.A. 83.7 80.1 44.1 N.A. 41 55.8 38.5 38.4
P-Site Identity: 100 93.3 86.6 86.6 N.A. 86.6 13.3 N.A. N.A. 86.6 66.6 6.6 N.A. 13.3 13.3 13.3 0
P-Site Similarity: 100 100 93.3 93.3 N.A. 93.3 26.6 N.A. N.A. 93.3 73.3 40 N.A. 26.6 13.3 20 20
Percent
Protein Identity: 31.9 N.A. N.A. 30.6 N.A. 26.6
Protein Similarity: 50 N.A. N.A. 49.1 N.A. 44
P-Site Identity: 6.6 N.A. N.A. 13.3 N.A. 13.3
P-Site Similarity: 20 N.A. N.A. 33.3 N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 7 7 7 50 44 7 7 7 44 % A
% Cys: 7 0 0 0 0 25 7 0 0 0 7 0 0 0 7 % C
% Asp: 0 7 0 7 7 0 0 0 0 7 0 0 0 7 0 % D
% Glu: 57 7 0 7 0 19 0 19 44 0 0 0 7 13 13 % E
% Phe: 0 0 7 7 0 0 0 7 0 0 7 0 7 0 0 % F
% Gly: 7 19 0 7 13 38 7 7 0 7 7 38 0 7 0 % G
% His: 0 7 0 7 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 19 0 0 0 0 0 7 0 0 % I
% Lys: 0 50 0 0 7 0 0 7 13 0 0 0 7 7 7 % K
% Leu: 7 0 57 7 7 0 50 0 0 7 7 7 7 7 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % M
% Asn: 0 0 0 7 13 0 7 0 7 0 7 7 0 0 0 % N
% Pro: 0 0 7 0 0 0 0 0 7 0 0 0 0 0 0 % P
% Gln: 7 0 7 7 0 7 0 7 7 7 7 7 50 0 0 % Q
% Arg: 7 13 0 0 44 7 7 7 7 7 7 0 0 0 0 % R
% Ser: 7 0 7 44 7 0 0 44 13 7 7 7 0 7 7 % S
% Thr: 0 0 0 0 0 7 0 0 0 7 0 13 13 50 13 % T
% Val: 7 0 13 7 7 0 0 0 0 0 7 13 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _